Cancer-miRNA Regulatory Network

Compendium of miRNA Target Genes

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CA Colon Graudens Cluster Number 40 (70 genes) This page contains all miRNA mediated regulation and functional enrichment for CA Colon Graudens cluster number 40. Information about colon cancer can be found on Wikipedia, and further information about the "CA Colon Graudens" dataset can be found in Graudens et al., 2006. Inferred miRNA Mediated Regulation Weeder-miRvestigator PITA TargetScan zzz999 hsa-mir-507 hsa-mir-557 hsa-mir-369-3p Gene Ontology Enrichment GO ID GO Term Annotated Genes in Cluster GO:0002376 immune system process 21 GO:0002682 regulation of immune system process 13 GO:0002684 positive regulation of immune system process 10 GO:0002756 MyD88-independent toll-like receptor signaling pathway 5 GO:0006464 protein modification process 24 GO:0006915 apoptosis 21 GO:0006950 response to stress 31 GO:0008063 Toll signaling pathway 5 GO:0008219 cell death 22 GO:0008283 cell proliferation 24 GO:0008285 negative regulation of cell proliferation 11 GO:0009611 response to wounding 15 GO:0012501 programmed cell death 21 GO:0016265 death 22 GO:0019538 protein metabolic process 31 GO:0034138 toll-like receptor 3 signaling pathway 5 GO:0034142 toll-like receptor 4 signaling pathway 5 GO:0042127 regulation of cell proliferation 19 GO:0042981 regulation of apoptosis 17 GO:0043067 regulation of programmed cell death 17 GO:0043412 macromolecule modification 24 GO:0048518 positive regulation of biological process 32 GO:0048519 negative regulation of biological process 28 GO:0048522 positive regulation of cellular process 27 GO:0048523 negative regulation of cellular process 27 GO:0050896 response to stimulus 47 Overlap Between miRNA Target Genes and Enriched Gene Ontology Annotations miRNA Method GO ID GO Term Overlap GO Annotated Genes Cluster Size miRNA Targets Genes P-Value hsa-mir-507 PITA GO:0002376 immune system process 1 21 70 7 0.6833761 hsa-mir-557 PITA GO:0002376 immune system process 1 21 70 7 0.6833761 hsa-mir-369-3p TargetScan GO:0002376 immune system process 7 21 70 23 0.3654578 hsa-mir-507 PITA GO:0002682 regulation of immune system process 1 13 70 7 0.3859287 hsa-mir-557 PITA GO:0002682 regulation of immune system process 1 13 70 7 0.3859287 hsa-mir-369-3p TargetScan GO:0002682 regulation of immune system process 4 13 70 23 0.431473 hsa-mir-507 PITA GO:0002684 positive regulation of immune system process 0 10 70 7 0.6778319 hsa-mir-557 PITA GO:0002684 positive regulation of immune system process 0 10 70 7 0.6778319 hsa-mir-369-3p TargetScan GO:0002684 positive regulation of immune system process 3 10 70 23 0.4266322 hsa-mir-507 PITA GO:0002756 MyD88-independent toll-like receptor signaling pathway 0 5 70 7 0.4192482 hsa-mir-557 PITA GO:0002756 MyD88-independent toll-like receptor signaling pathway 0 5 70 7 0.4192482 hsa-mir-369-3p TargetScan GO:0002756 MyD88-independent toll-like receptor signaling pathway 2 5 70 23 0.1953468 hsa-mir-507 PITA GO:0006464 protein modification process 3 24 70 7 0.176707 hsa-mir-557 PITA GO:0006464 protein modification process 3 24 70 7 0.176707 hsa-mir-369-3p TargetScan GO:0006464 protein modification process 10 24 70 23 0.08144746 hsa-mir-507 PITA GO:0006915 apoptosis 2 21 70 7 0.3493303 hsa-mir-557 PITA GO:0006915 apoptosis 2 21 70 7 0.3493303 hsa-mir-369-3p TargetScan GO:0006915 apoptosis 8 21 70 23 0.1865041 hsa-mir-507 PITA GO:0006950 response to stress 3 31 70 7 0.3710516 hsa-mir-557 PITA GO:0006950 response to stress 3 31 70 7 0.3710516 hsa-mir-369-3p TargetScan GO:0006950 response to stress 6 31 70 23 0.9717179 hsa-mir-507 PITA GO:0008063 Toll signaling pathway 0 5 70 7 0.4192482 hsa-mir-557 PITA GO:0008063 Toll signaling pathway 0 5 70 7 0.4192482 hsa-mir-369-3p TargetScan GO:0008063 Toll signaling pathway 2 5 70 23 0.1953468 hsa-mir-507 PITA GO:0008219 cell death 2 22 70 7 0.3834166 hsa-mir-557 PITA GO:0008219 cell death 2 22 70 7 0.3834166 hsa-mir-369-3p TargetScan GO:0008219 cell death 8 22 70 23 0.2412858 hsa-mir-507 PITA GO:0008283 cell proliferation 3 24 70 7 0.176707 hsa-mir-557 PITA GO:0008283 cell proliferation 3 24 70 7 0.176707 hsa-mir-369-3p TargetScan GO:0008283 cell proliferation 6 24 70 23 0.7695217 hsa-mir-507 PITA GO:0008285 negative regulation of cell proliferation 1 11 70 7 0.3019692 hsa-mir-557 PITA GO:0008285 negative regulation of cell proliferation 1 11 70 7 0.3019692 hsa-mir-369-3p TargetScan GO:0008285 negative regulation of cell proliferation 5 11 70 23 0.09587707 hsa-mir-507 PITA GO:0009611 response to wounding 1 15 70 7 0.4679794 hsa-mir-557 PITA GO:0009611 response to wounding 1 15 70 7 0.4679794 hsa-mir-369-3p TargetScan GO:0009611 response to wounding 2 15 70 23 0.9387362 hsa-mir-507 PITA GO:0012501 programmed cell death 2 21 70 7 0.3493303 hsa-mir-557 PITA GO:0012501 programmed cell death 2 21 70 7 0.3493303 hsa-mir-369-3p TargetScan GO:0012501 programmed cell death 8 21 70 23 0.1865041 hsa-mir-507 PITA GO:0016265 death 2 22 70 7 0.3834166 hsa-mir-557 PITA GO:0016265 death 2 22 70 7 0.3834166 hsa-mir-369-3p TargetScan GO:0016265 death 8 22 70 23 0.2412858 hsa-mir-507 PITA GO:0019538 protein metabolic process 3 31 70 7 0.3710516 hsa-mir-557 PITA GO:0019538 protein metabolic process 3 31 70 7 0.3710516 hsa-mir-369-3p TargetScan GO:0019538 protein metabolic process 11 31 70 23 0.25003 hsa-mir-507 PITA GO:0034138 toll-like receptor 3 signaling pathway 0 5 70 7 0.4192482 hsa-mir-557 PITA GO:0034138 toll-like receptor 3 signaling pathway 0 5 70 7 0.4192482 hsa-mir-369-3p TargetScan GO:0034138 toll-like receptor 3 signaling pathway 2 5 70 23 0.1953468 hsa-mir-507 PITA GO:0034142 toll-like receptor 4 signaling pathway 0 5 70 7 0.4192482 hsa-mir-557 PITA GO:0034142 toll-like receptor 4 signaling pathway 0 5 70 7 0.4192482 hsa-mir-369-3p TargetScan GO:0034142 toll-like receptor 4 signaling pathway 2 5 70 23 0.1953468 hsa-mir-507 PITA GO:0042127 regulation of cell proliferation 3 19 70 7 0.0808972 hsa-mir-557 PITA GO:0042127 regulation of cell proliferation 3 19 70 7 0.0808972 hsa-mir-369-3p TargetScan GO:0042127 regulation of cell proliferation 6 19 70 23 0.435761 hsa-mir-507 PITA GO:0042981 regulation of apoptosis 1 17 70 7 0.5458528 hsa-mir-557 PITA GO:0042981 regulation of apoptosis 1 17 70 7 0.5458528 hsa-mir-369-3p TargetScan GO:0042981 regulation of apoptosis 6 17 70 23 0.2898348 hsa-mir-507 PITA GO:0043067 regulation of programmed cell death 1 17 70 7 0.5458528 hsa-mir-557 PITA GO:0043067 regulation of programmed cell death 1 17 70 7 0.5458528 hsa-mir-369-3p TargetScan GO:0043067 regulation of programmed cell death 6 17 70 23 0.2898348 hsa-mir-507 PITA GO:0043412 macromolecule modification 3 24 70 7 0.176707 hsa-mir-557 PITA GO:0043412 macromolecule modification 3 24 70 7 0.176707 hsa-mir-369-3p TargetScan GO:0043412 macromolecule modification 10 24 70 23 0.08144746 hsa-mir-507 PITA GO:0048518 positive regulation of biological process 3 32 70 7 0.4026837 hsa-mir-557 PITA GO:0048518 positive regulation of biological process 3 32 70 7 0.4026837 hsa-mir-369-3p TargetScan GO:0048518 positive regulation of biological process 8 32 70 23 0.848246 hsa-mir-507 PITA GO:0048519 negative regulation of biological process 5 28 70 7 0.01418709 hsa-mir-557 PITA GO:0048519 negative regulation of biological process 5 28 70 7 0.01418709 hsa-mir-369-3p TargetScan GO:0048519 negative regulation of biological process 10 28 70 23 0.2489565 hsa-mir-507 PITA GO:0048522 positive regulation of cellular process 3 27 70 7 0.2528417 hsa-mir-557 PITA GO:0048522 positive regulation of cellular process 3 27 70 7 0.2528417 hsa-mir-369-3p TargetScan GO:0048522 positive regulation of cellular process 7 27 70 23 0.7619289 hsa-mir-507 PITA GO:0048523 negative regulation of cellular process 5 27 70 7 0.01135865 hsa-mir-557 PITA GO:0048523 negative regulation of cellular process 5 27 70 7 0.01135865 hsa-mir-369-3p TargetScan GO:0048523 negative regulation of cellular process 10 27 70 23 0.1968863 hsa-mir-507 PITA GO:0050896 response to stimulus 3 47 70 7 0.8457191 hsa-mir-557 PITA GO:0050896 response to stimulus 3 47 70 7 0.8457191 hsa-mir-369-3p TargetScan GO:0050896 response to stimulus 14 47 70 23 0.6977369

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